The effect of therapeutic feed additive on rumen fermentation in cows with ketosis

It is known that ionophoric antibiotics regulate ruminal fermentation, improve the utilization of feed protein, and prevent occurrence ketosis steatosis in ruminants. Ionophoric β-acids hops have a similar spectrum biological activity, is, they inhibit vital activity most gram-positive microorganisms rumen. Bacteria, like other living organisms, need vitamin E as an active antioxidant for cell membranes. The toxicity tocopherol very low, so adding it to diet ruminants larger quantities can stimulate celluloselytic rumen bacteria compensate negative effect ionophores on fiber breakdown. Since break down significant part dietary choline, methionine carnitine, must receive them protected form, their influence fermentation insignificant. Three groups cows Ukrainian dairy black-spotted breed with milk yields 5 or more thousand kg during previous lactation were formed: signs clinical — 4 animals; subclinical animals clinically healthy animals. For month, given treatment supplement containing crushed granules hop cones (20 g), (3 choline (50 g) carnitine (1 g). Clinically used control. In blood ketosis, additive increased concentration glucose decreased β-hydroxybutyrate, these indicators within normal range. symptoms using also reduced β-hydroxybutyrate (P<0.01), but was still higher than normal. sick cows, amylolytic lipolytic lower (P<0.05–0.01). Celluloselytic only ketosis. proteolytic content changed opposite way; This consequence increase number hyper producing ammonia rumen, what characteristic After activities fluid equal corresponding even slightly (P<0.05) control group. Treatment form not effective, although general trends remained. During greater amount found (P<0.05–0.01), because activity. both forms volatile fatty acids decreased, lactate treatment, approached animals, while condition improved, continued differ from